DKK1 Positive Control
Catalog no. PC-DKK1 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-DKK1 — affinity-purified Rabbit antibody against DKK1. Validated for WB.
Specifications
| Catalog number | PC-DKK1 |
|---|---|
| Target | DKK1 |
| Applications | WB |
| Conjugate | Unconjugated |
| Immunogen | Cell lysate / recombinant protein fraction positive for DKK1. |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | O94907 |
About this target
DKK1 Positive Control is a Western blot positive control for DKK1 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease. Inhibits the pro-apoptotic function of KREMEN1 in a Wnt-independent manner, and has anti-apoptotic activity. Subcellular location: Secreted.
Documents
Related products
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- DKK1 Antibody BIOTIN (DKK1-BIOTIN)
- DKK1 Antibody FITC (DKK1-FITC)
- DKK1 Blocking Peptide (P-DKK1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.