Dnmt1 Antibody
Catalog no. DNMT1-101AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
DNMT1-101AP — affinity purified Rabbit antibody against Dnmt1. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | DNMT1-101AP |
|---|---|
| Target | Dnmt1 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 1550-1600 on human Dnmt1 protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P26358 |
About this target
Dnmt1 Antibody (DNMT1-101AP) is an affinity-purified rabbit polyclonal antibody against Dnmt1. It is listed for ELISA, IP, WB and reacts with Human, Mouse, Rat. For research use only. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. Subcellular location: Nucleus. Chromosome.
Documents
Related products
- Dnmt1 Antibody BIOTIN (DNMT1-BIOTIN)
- Dnmt1 Antibody FITC (DNMT1-FITC)
- Dnmt1 Blocking Peptide (P-DNMT1)
- Dnmt1 Positive Control (PC-DNMT1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.