Dnmt1 Antibody BIOTIN

Catalog no. DNMT1-BIOTIN · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

DNMT1-BIOTIN — affinity purified Rabbit antibody against Dnmt1. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberDNMT1-BIOTIN
TargetDnmt1
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IP, WB
ConjugateBIOTIN
PurityAffinity Purified
ImmunogenSynthetic peptide corresponding to amino acids within region 1550-1600 on human Dnmt1 protein.
Size100 µg
Storage-20°C
UniProtP26358

About this target

Dnmt1 Antibody BIOTIN is the biotin-conjugated version of the Dnmt1 antibody DNMT1-101AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. DNA methyltransferase that methylates CpG residues. Preferentially methylates hemimethylated DNA. Associates with DNA replication sites in S phase maintaining the methylation pattern in the newly synthesized strand, that is essential for epigenetic inheritance. Associates with chromatin during G2 and M phases to maintain DNA methylation independently of replication. It is responsible for maintaining methylation patterns established in development. DNA methylation is coordinated with methylation of histones. Mediates transcriptional repression by direct binding to HDAC2. Subcellular location: Nucleus. Chromosome.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.