Dnmt3L Antibody
Catalog no. DNMT3L-101AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
DNMT3L-101AP — affinity purified Rabbit antibody against Dnmt3L. Validated for ELISA, IP, WB. Reacts with Mouse, Rat.
Specifications
| Catalog number | DNMT3L-101AP |
|---|---|
| Target | Dnmt3L |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 372-421 on mouse DNA (cytosine-5)-methyltransferase 3-like protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q9CWR8 |
About this target
Dnmt3L Antibody (DNMT3L-101AP) is an affinity-purified rabbit polyclonal antibody against Dnmt3L. It is listed for ELISA, IP, WB and reacts with Mouse, Rat. For research use only. Catalytically inactive regulatory factor of DNA methyltransferases that can either promote or inhibit DNA methylation depending on the context. Essential for the function of DNMT3A and DNMT3B: activates DNMT3A and DNMT3B by binding to their catalytic domain. Acts by accelerating the binding of DNA and S-adenosyl-L-methionine (AdoMet) to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4me0) and induces de novo DNA methylation by recruitment or activation of DNMT3. Subcellular location: Nucleus.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.