Dnmt3L Positive Control
Catalog no. PC-DNMT3L · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-DNMT3L — affinity-purified Rabbit antibody against Dnmt3L. Validated for WB.
Specifications
| Catalog number | PC-DNMT3L |
|---|---|
| Target | Dnmt3L |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q9CWR8 |
About this target
Dnmt3L Positive Control is a Western blot positive control for Dnmt3L antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Catalytically inactive regulatory factor of DNA methyltransferases that can either promote or inhibit DNA methylation depending on the context. Essential for the function of DNMT3A and DNMT3B: activates DNMT3A and DNMT3B by binding to their catalytic domain. Acts by accelerating the binding of DNA and S-adenosyl-L-methionine (AdoMet) to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4me0) and induces de novo DNA methylation by recruitment or activation of DNMT3. Subcellular location: Nucleus.
Documents
Related products
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- Dnmt3L Blocking Peptide (P-DNMT3L)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.