IL18 Positive Control
Catalog no. PC-IL18 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-IL18 — affinity-purified Rabbit antibody against IL18. Validated for WB.
Specifications
| Catalog number | PC-IL18 |
|---|---|
| Target | IL18 |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q14116 |
About this target
IL18 Positive Control is a Western blot positive control for IL18 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Pro-inflammatory cytokine primarily involved in epithelial barrier repair, polarized T-helper 1 (Th1) cell and natural killer (NK) cell immune responses. Upon binding to IL18R1 and IL18RAP, forms a signaling ternary complex which activates NF-kappa-B, triggering synthesis of inflammatory mediators. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells and natural killer (NK) cells. Involved in transduction of inflammation downstream of pyroptosis: its mature form is specifically released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore. Subcellular location: Cytoplasm, cytosol. Secreted. Note=The precursor is cytosolic. In response to inflammasome-activating signals, cleaved and secreted. Mature form is secreted and released in the extracellular milieu by passing through the gasdermin-D (GSDMD) pore.
Documents
Related products
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- IL18 Antibody BIOTIN (IL18-BIOTIN)
- IL18 Antibody FITC (IL18-FITC)
- IL18 Blocking Peptide (P-IL18)
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.