MeCP2 isoform 1 Positive Control

Catalog no. PC-MECP2E1 · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-MECP2E1 — affinity-purified Rabbit antibody against MeCP2 isoform 1. Validated for WB.

Specifications

Catalog numberPC-MECP2E1
TargetMeCP2 isoform 1
ApplicationsWB
ConjugateUnconjugated
ImmunogenPurified Protein
Size5 applications
Storage-20°C
UniProtP51608

About this target

Chromosomal protein that binds to methylated DNA. It can bind specifically to a single methyl-CpG pair. It is not influenced by sequences flanking the methyl-CpGs. Mediates transcriptional repression through interaction with histone deacetylase and the co. Interacts with FNBP3 (By similarity). Interacts with CDKL5 (PubMed:15917271). Interacts with ATRX; MECP2 recruits ATRX to pericentric heterochromatin in neuronal cells (By similarity). Interacts with NCOR2 (By similarity). Subcellular location: Nucleus (Note: Colocalized with methyl-CpG in the genome). Expression: Present in all adult somatic tissues tested.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.