NEDD8 Antibody
Catalog no. NEDD8-101AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
NEDD8-101AP — affinity purified Rabbit antibody against NEDD8. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | NEDD8-101AP |
|---|---|
| Target | NEDD8 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 32-81 on human NEDD8 protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q15843 |
About this target
NEDD8 Antibody (NEDD8-101AP) is an affinity-purified rabbit polyclonal antibody against NEDD8. It is listed for ELISA, IP, WB and reacts with Human, Mouse, Rat. For research use only. Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity. Subcellular location: Nucleus. Note=Mainly nuclear.
Documents
Related products
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- NEDD8 Antibody FITC (NEDD8-FITC)
- NEDD8 Blocking Peptide (P-NEDD8)
- NEDD8 Positive Control (PC-NEDD8)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.