NEDD8 Blocking Peptide
Catalog no. P-NEDD8 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-NEDD8 — affinity-purified Rabbit antibody against NEDD8. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-NEDD8 |
|---|---|
| Target | NEDD8 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 32-81 on human NEDD8 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q15843 |
About this target
NEDD8 Blocking Peptide is the antigenic blocking peptide for the NEDD8 antibody NEDD8-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis via its conjugation to a limited number of cellular proteins, such as cullins or p53/TP53. Attachment of NEDD8 to cullins is critical for the recruitment of E2 to the cullin-RING-based E3 ubiquitin-protein ligase complex, thus facilitating polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins. Attachment of NEDD8 to p53/TP53 inhibits p53/TP53 transcriptional activity. Subcellular location: Nucleus. Note=Mainly nuclear.
Documents
Related products
- NEDD8 Antibody (NEDD8-101AP)
- NEDD8 Antibody BIOTIN (NEDD8-BIOTIN)
- NEDD8 Antibody FITC (NEDD8-FITC)
- NEDD8 Positive Control (PC-NEDD8)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.