PARP1 BIOTIN
Catalog no. PARP1-BIOTIN · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
PARP1-BIOTIN — affinity purified Rabbit antibody against PARP1. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | PARP1-BIOTIN |
|---|---|
| Target | PARP1 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 870-920 on human Poly ADP-ribose polymerase 1 protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P09874 |
About this target
PARP1 BIOTIN is the biotin-conjugated version of the PARP1 antibody PARP1-101AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. Subcellular location: Chromosome. Nucleus. Nucleus, nucleolus. Cytoplasm, cytosol. Note=Localizes to sites of DNA damage. Recognizes (via PARP-type zinc-fingers) and binds DNA strand breaks. Also binds normal/undamaged chromatin.
Documents
Related products
- PARP1 Blocking Peptide (P-PARP1)
- PARP1 Antibody (PARP1-101AP)
- PARP1 FITC (PARP1-FITC)
- PARP1 Positive Control (PC-PARP1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.