PARP1 Blocking Peptide
Catalog no. P-PARP1 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-PARP1 — affinity-purified Rabbit antibody against PARP1. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-PARP1 |
|---|---|
| Target | PARP1 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 870-920 on human Poly ADP-ribose polymerase 1 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P09874 |
About this target
PARP1 Blocking Peptide is the antigenic blocking peptide for the PARP1 antibody PARP1-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Poly-ADP-ribosyltransferase that mediates poly-ADP-ribosylation of proteins and plays a key role in DNA repair. Mediates glutamate, aspartate, serine, histidine or tyrosine ADP-ribosylation of proteins: the ADP-D-ribosyl group of NAD(+) is transferred to the acceptor carboxyl group of target residues and further ADP-ribosyl groups are transferred to the 2'-position of the terminal adenosine moiety, building up a polymer with an average chain length of 20-30 units. Serine ADP-ribosylation of proteins constitutes the primary form of ADP-ribosylation of proteins in response to DNA damage. Subcellular location: Chromosome. Nucleus. Nucleus, nucleolus. Cytoplasm, cytosol. Note=Localizes to sites of DNA damage. Recognizes (via PARP-type zinc-fingers) and binds DNA strand breaks. Also binds normal/undamaged chromatin.
Documents
Related products
- PARP1 Antibody (PARP1-101AP)
- PARP1 BIOTIN (PARP1-BIOTIN)
- PARP1 FITC (PARP1-FITC)
- PARP1 Positive Control (PC-PARP1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.