Phospho-Androgen Receptor Antibody BIOTIN
Catalog no. PANDR-BIOTIN · Research Use Only
$425 per 100 µg. Ships within 2–3 business days from the U.S.
PANDR-BIOTIN — affinity purified Rabbit antibody against Phospho-Androgen Receptor. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | PANDR-BIOTIN |
|---|---|
| Target | Phospho-Androgen Receptor |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 550-600 on Human Androgen Receptor. Phospho Serine 568. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P10275 |
About this target
Phospho-Androgen Receptor Antibody BIOTIN is the biotin-conjugated version of the Phospho-Androgen Receptor antibody PANDR-140AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Subcellular location: Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.
Documents
Related products
- Phospho-Androgen Receptor Blocking Peptide (P-PANDR)
- Phospho-Androgen Receptor Antibody (PANDR-140AP)
- Phospho-Androgen Receptor Antibody FITC (PANDR-FITC)
- Phospho-Androgen Receptor Positive Control (PC-PANDR)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.