Phospho-Androgen Receptor Positive Control

Catalog no. PC-PANDR · Research Use Only

$220 per 5 applications. Ships within 2–3 business days from the U.S.

PC-PANDR — affinity-purified Rabbit antibody against Phospho-Androgen Receptor. Validated for WB.

Specifications

Catalog numberPC-PANDR
TargetPhospho-Androgen Receptor
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtP10275

About this target

Phospho-Androgen Receptor Positive Control is a Western blot positive control for Phospho-Androgen Receptor antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Steroid hormone receptors are ligand-activated transcription factors that regulate eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. Transcription factor activity is modulated by bound coactivator and corepressor proteins like ZBTB7A that recruits NCOR1 and NCOR2 to the androgen response elements/ARE on target genes, negatively regulating androgen receptor signaling and androgen-induced cell proliferation. Transcription activation is also down-regulated by NR0B2. Subcellular location: Nucleus. Cytoplasm. Note=Detected at the promoter of target genes. Predominantly cytoplasmic in unligated form but translocates to the nucleus upon ligand-binding. Can also translocate to the nucleus in unligated form in the presence of RACK1.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.