Phospho-PRP19 Antibody BIOTIN

Catalog no. PPRP19F-BIOTIN · Research Use Only

$425 per 100 µg. Ships within 2–3 business days from the U.S.

PPRP19F-BIOTIN — affinity purified Rabbit antibody against Phospho-PRP19. Validated for ELISA, WB. Reacts with Human, Mouse.

Specifications

Catalog numberPPRP19F-BIOTIN
TargetPhospho-PRP19
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse
ApplicationsELISA, WB
ConjugateBIOTIN
PurityAffinity Purified
ImmunogenPhosphorylated synthetic peptide taken within amino acid region 200-300 on rat PRP19F protein.
Size100 µg
Storage-20°C
UniProtQ9JMJ4

About this target

Phospho-PRP19 Antibody BIOTIN is the biotin-conjugated version of the Phospho-PRP19 antibody PPRP19F-140AP, an affinity-purified rabbit polyclonal used in ELISA, WB and reactive with Human, Mouse. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Subcellular location: Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Lipid droplet. Note=Nucleoplasmic in interphase cells. Irregularly distributed in anaphase cells.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.