Phospho-PRP19 Positive Control

Catalog no. PC-PPRP19F · Research Use Only

$220 per 5 applications. Ships within 2–3 business days from the U.S.

PC-PPRP19F — affinity-purified Rabbit antibody against Phospho-PRP19. Validated for WB.

Specifications

Catalog numberPC-PPRP19F
TargetPhospho-PRP19
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtQ9JMJ4

About this target

Phospho-PRP19 Positive Control is a Western blot positive control for Phospho-PRP19 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Ubiquitin-protein ligase which is a core component of several complexes mainly involved pre-mRNA splicing and DNA repair. Required for pre-mRNA splicing as component of the spliceosome. Core component of the PRP19C/Prp19 complex/NTC/Nineteen complex which is part of the spliceosome and participates in its assembly, its remodeling and is required for its activity. During assembly of the spliceosome, mediates 'Lys-63'-linked polyubiquitination of the U4 spliceosomal protein PRPF3. Ubiquitination of PRPF3 allows its recognition by the U5 component PRPF8 and stabilizes the U4/U5/U6 tri-snRNP spliceosomal complex. Subcellular location: Nucleus. Nucleus, nucleoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm. Lipid droplet. Note=Nucleoplasmic in interphase cells. Irregularly distributed in anaphase cells.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.