SETDB1 Blocking Peptide
Catalog no. P-SETDB1 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-SETDB1 — affinity-purified Rabbit antibody against SETDB1. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-SETDB1 |
|---|---|
| Target | SETDB1 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 51-100 of human SETDB1 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q15047 |
About this target
SETDB1 Blocking Peptide is the antigenic blocking peptide for the SETDB1 antibody SETDB1-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Subcellular location: Nucleus. Cytoplasm. Chromosome. Note=Associated with non-pericentromeric regions of chromatin. Recruited to H3K9me and H3K19ac marks on chromatin. Excluded from nucleoli and islands of condensed chromatin.
Documents
Related products
- SETDB1 Antibody (SETDB1-101AP)
- SETDB1 Antibody BIOTIN (SETDB1-BIOTIN)
- SETDB1 Antibody FITC (SETDB1-FITC)
- SETDB1 Positive Control (PC-SETDB1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.