SETDB1 Positive Control
Catalog no. PC-SETDB1 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-SETDB1 — affinity-purified Rabbit antibody against SETDB1. Validated for WB.
Specifications
| Catalog number | PC-SETDB1 |
|---|---|
| Target | SETDB1 |
| Applications | WB |
| Conjugate | Unconjugated |
| Immunogen | Cell lysate / recombinant protein fraction positive for SETDB1. |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q15047 |
About this target
SETDB1 Positive Control is a Western blot positive control for SETDB1 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Histone methyltransferase that specifically trimethylates 'Lys-9' of histone H3 (H3K9me3). H3 'Lys-9' trimethylation represents a specific tag for epigenetic transcriptional repression by recruiting HP1 (CBX1, CBX3 and/or CBX5) proteins to methylated histones. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. H3 'Lys-9' trimethylation is coordinated with DNA methylation. Forms a complex with MBD1 and ATF7IP that represses transcription and couples DNA methylation and histone 'Lys-9' trimethylation. Subcellular location: Nucleus. Cytoplasm. Chromosome. Note=Associated with non-pericentromeric regions of chromatin. Recruited to H3K9me and H3K19ac marks on chromatin. Excluded from nucleoli and islands of condensed chromatin.
Documents
Related products
- SETDB1 Antibody (SETDB1-101AP)
- SETDB1 Antibody BIOTIN (SETDB1-BIOTIN)
- SETDB1 Antibody FITC (SETDB1-FITC)
- SETDB1 Blocking Peptide (P-SETDB1)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.