TLR5 Antibody
Catalog no. TLR-501AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
TLR-501AP — affinity purified Rabbit antibody against TLR5. Validated for ELISA, IP, WB. Reacts with Human.
Specifications
| Catalog number | TLR-501AP |
|---|---|
| Target | TLR5 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 191-240 on human TLR5 protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | O60602 |
About this target
Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Binds MYD88 via their respective TIR domains (By similarity). Homodimer both in the absence and presence of ligand. Subcellular location: Membrane; Single-pass type I membrane protein. Expression: Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.
Documents
Related products
- TLR5 Blocking Peptide (P-TLR5)
- TLR5 Positive Control (PC-TLR5)
- TLR5 Antibody BIOTIN (TLR5-BIOTIN)
- TLR5 Antibody FITC (TLR5-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.