TLR5 Antibody FITC

Catalog no. TLR5-FITC · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

TLR5-FITC — affinity purified Rabbit antibody against TLR5. Validated for ELISA, IP, WB. Reacts with Human.

Specifications

Catalog numberTLR5-FITC
TargetTLR5
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman
ApplicationsELISA, IP, WB
ConjugateFITC
PurityAffinity Purified
ImmunogenSynthetic peptide taken within amino acid region 191-240 on human TLR5 protein.
Size100 µg
Storage-20°C
UniProtO60602

About this target

Participates in the innate immune response to microbial agents. Mediates detection of bacterial flagellins. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Binds MYD88 via their respective TIR domains (By similarity). Homodimer both in the absence and presence of ligand. Subcellular location: Membrane; Single-pass type I membrane protein. Expression: Highly expressed in ovary and in peripheral blood leukocytes, especially in monocytes, less in CD11c+ immature dendritic cells. Also detected in prostate and testis.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.