TNF alpha Blocking Peptide
Catalog no. P-TNFA · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-TNFA — affinity-purified Rabbit antibody against TNF alpha. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-TNFA |
|---|---|
| Target | TNF alpha |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 100-150 on human Tumor necrosis factor alpha protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P01375 |
About this target
TNF alpha Blocking Peptide is the antigenic blocking peptide for the TNF alpha antibody TNFA-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Subcellular location: Cell membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted.; SUBCELLULAR LOCATION:
Documents
Related products
- TNF alpha Positive Control (PC-TNFA)
- TNF alpha Antibody (TNFA-101AP)
- TNF alpha Antibody BIOTIN (TNFA-BIOTIN)
- TNF alpha Antibody FITC (TNFA-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.