TNF alpha Positive Control

Catalog no. PC-TNFA · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-TNFA — affinity-purified Rabbit antibody against TNF alpha. Validated for WB.

Specifications

Catalog numberPC-TNFA
TargetTNF alpha
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtP01375

About this target

TNF alpha Positive Control is a Western blot positive control for TNF alpha antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Cytokine that binds to TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. It is mainly secreted by macrophages and can induce cell death of certain tumor cell lines. It is potent pyrogen causing fever by direct action or by stimulation of interleukin-1 secretion and is implicated in the induction of cachexia, Under certain conditions it can stimulate cell proliferation and induce cell differentiation. Impairs regulatory T-cells (Treg) function in individuals with rheumatoid arthritis via FOXP3 dephosphorylation. Subcellular location: Cell membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor, membrane form]: Membrane; Single-pass type II membrane protein.; SUBCELLULAR LOCATION: [Tumor necrosis factor, soluble form]: Secreted.; SUBCELLULAR LOCATION:

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.