Topoisomerase II alpha Antibody
Catalog no. TOPO2A-201AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
TOPO2A-201AP — affinity purified Rabbit antibody against Topoisomerase II alpha. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | TOPO2A-201AP |
|---|---|
| Target | Topoisomerase II alpha |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 1220-1270 on human DNA topoisomerase (ATP-hydrolysing) protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P11388 |
About this target
Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. Homodimer. Interacts with COPS5. Interacts with RECQL5; this stimulates DNA decatenation. Interacts with SETMAR; stimulates the topoisomerase activity. Subcellular location: Cytoplasm, Nucleus.
Documents
Related products
- Topoisomerase II alpha Blocking Peptide (P-TOPO2A)
- Topoisomerase II alpha Positive Control (PC-TOPO2A)
- Topoisomerase II alpha Antibody BIOTIN (TOPO2A-BIOTIN)
- Topoisomerase II alpha Antibody FITC (TOPO2A-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.