Topoisomerase II alpha Positive Control

Catalog no. PC-TOPO2A · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-TOPO2A — affinity-purified Rabbit antibody against Topoisomerase II alpha. Validated for WB.

Specifications

Catalog numberPC-TOPO2A
TargetTopoisomerase II alpha
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtP11388

About this target

Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. Homodimer. Interacts with COPS5. Interacts with RECQL5; this stimulates DNA decatenation. Interacts with SETMAR; stimulates the topoisomerase activity. Subcellular location: Cytoplasm, Nucleus.

Documents

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.