Triggering receptor expressed on myeloid cells 1 Antibody Positve Control

Catalog no. PC-TREM1 · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-TREM1 — affinity-purified Rabbit antibody against TREM1. Validated for WB.

Specifications

Catalog numberPC-TREM1
TargetTREM1
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtQ9NP99

About this target

Triggering receptor expressed on myeloid cells 1 Antibody Positve Control is a Western blot positive control for TREM1 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. [Isoform 1]: Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=Recruited to lipid rafts when activated.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.