Triggering receptor expressed on myeloid cells 1 Blocking Peptide
Catalog no. P-TREM1 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-TREM1 — affinity-purified Rabbit antibody against TREM1. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-TREM1 |
|---|---|
| Target | TREM1 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 96-145 on Triggering receptor expressed on myeloid cells 1 protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q9NP99 |
About this target
Triggering receptor expressed on myeloid cells 1 Blocking Peptide is the antigenic blocking peptide for the TREM1 antibody TREM1-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. [Isoform 1]: Cell surface receptor that plays important roles in innate and adaptive immunity by amplifying inflammatory responses. Upon activation by various ligands such as PGLYRP1, HMGB1 or HSP70, multimerizes and forms a complex with transmembrane adapter TYROBP/DAP12. In turn, initiates a SYK-mediated cascade of tyrosine phosphorylation, activating multiple downstream mediators such as BTK, MAPK1, MAPK3 or phospholipase C-gamma. Subcellular location: [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Note=Recruited to lipid rafts when activated.; SUBCELLULAR LOCATION: [Isoform 2]: Secreted.
Documents
Related products
- Triggering receptor expressed on myeloid cells 1 Antibody Positve Control (PC-TREM1)
- Triggering receptor expressed on myeloid cells 1 Antibody (TREM1-101AP)
- Triggering receptor expressed on myeloid cells 1 Antibody BIOTIN (TREM1-BIOTIN)
- Triggering receptor expressed on myeloid cells 1 Antibody FITC (TREM1-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.