xCT Antibody FITC

Catalog no. SLC7A11-FITC · Research Use Only

$375 per 100 µg. Ships within 2–3 business days from the U.S.

SLC7A11-FITC — affinity purified Rabbit antibody against xCT. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.

Specifications

Catalog numberSLC7A11-FITC
TargetxCT
HostRabbit
ClonalityPolyclonal
IsotypeIgG
ReactivityHuman, Mouse, Rat
ApplicationsELISA, IP, WB
ConjugateFITC
PurityAffinity Purified
ImmunogenSynthetic peptide corresponding to amino acids within region 275-325 on human SLC7A11 protein.
Size100 µg
Storage-20°C
UniProtQ9UPY5

About this target

xCT Antibody FITC is the FITC-conjugated version of the xCT antibody SLC7A11-101AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane. Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress. The transport is sodium-independent, electroneutral with a stoichiometry of 1:1, and is drove by the high intracellular concentration of L-glutamate and the intracellular reduction of L-cystine. Subcellular location: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Note=Localized to the microvillous membrane of the placental syncytiotrophoblast.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.