xCT Positive Control

Catalog no. PC-SLC7A11 · Research Use Only

$200 per 5 applications. Ships within 2–3 business days from the U.S.

PC-SLC7A11 — affinity-purified Rabbit antibody against xCT. Validated for WB.

Specifications

Catalog numberPC-SLC7A11
TargetxCT
ApplicationsWB
ConjugateUnconjugated
ImmunogenPartially purified human SLC7A11 protein.
Size5 applications
Storage-20°C
UniProtQ9UPY5

About this target

xCT Positive Control is a Western blot positive control for xCT antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Heterodimer with SLC3A2, that functions as an antiporter by mediating the exchange of extracellular anionic L-cystine and intracellular L-glutamate across the cellular plasma membrane. Provides L-cystine for the maintenance of the redox balance between extracellular L-cystine and L-cysteine and for the maintenance of the intracellular levels of glutathione that is essential for cells protection from oxidative stress. The transport is sodium-independent, electroneutral with a stoichiometry of 1:1, and is drove by the high intracellular concentration of L-glutamate and the intracellular reduction of L-cystine. Subcellular location: Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cell projection, microvillus membrane; Multi-pass membrane protein. Note=Localized to the microvillous membrane of the placental syncytiotrophoblast.

Documents

Related products

FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.