General Information |
|
Product |
SIGLEC10 Peptide |
Description |
Antigenic Blocking Peptide Sialic acid-binding Ig-like lectin 10 Antibody |
Verified Applications |
Immunocompetition, Immunodepletion |
Peptide Description |
Synthetic peptide taken within amino acid region 650-697 on human SIGLEC10 protein. |
Accession # |
NCBI: NP_149121.2 |
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|
Quantity |
250 µg |
Volume |
100 µl |
Form |
Antigenic Blocking Peptide |
Storage |
-20⁰C for long term storage |
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|
Competition/Depletion assay |
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|
Uniprot # |
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Overview |
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Molecular Function |
carbohydrate binding |
Subcellular Location |
Isoform 1,2,3,4: cell membrane, single-pass type I membrane protein; isoform 5: secreted |
Expression |
Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells. |
Alternative Nomenclature |
mSiglec G antibody, PRO940 antibody, Sialic acid binding Ig like lectin 10 antibody, sialic acid binding Ig like lectin G antibody, Sialic acid-binding Ig-like lectin 10 antibody, Siglec G antibody, Siglecg antibody, SLG2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
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SIGLEC10-101AP | |||
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SIGLEC10-FITC | |||
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SIGLEC10-BIOTIN | |||
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PC-SIGLEC10 | |||
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