GADD34 Antibody BIOTIN
Catalog no. GADD34-BIOTIN · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
GADD34-BIOTIN — affinity purified Rabbit antibody against GADD34. Validated for ELISA, IHC, IP, WB. Reacts with Bovine, Human, Monkey, Panda.
Specifications
| Catalog number | GADD34-BIOTIN |
|---|---|
| Target | GADD34 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Bovine, Human, Monkey, Panda |
| Applications | ELISA, IHC, IP, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | 75807 |
About this target
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. belongs to PPP1R15 family. Subcellular location: Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side. Expression: induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells.
Documents
Related products
- GADD34 Antibody (GADD34-101AP)
- GADD34 Antibody FITC (GADD34-FITC)
- GADD34 Blocking Peptide (P-GADD34)
- GADD34 Positive Control (PC-GADD34)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.