GADD34 Blocking Peptide
Catalog no. P-GADD34 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-GADD34 — affinity-purified Rabbit antibody against GADD34. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-GADD34 |
|---|---|
| Target | GADD34 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to internal sequence of amino acids 380-400 of Human GADD34, covalently modified and coupled to a carrier protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | 75807 |
About this target
Recruits serine/threonine-protein phosphatase PP1 to dephosphorylate translation initation factor eIF2A/EIF2S1. This reverses shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. belongs to PPP1R15 family. Subcellular location: Endoplasmic Reticulum membrane; Peripheral membrane protein; Cytoplasmic side; Mitochondrion outer membrane; Peripheral membrane protein; Cytoplasmic Side. Expression: induced by methyl methanesulfonate and ionizing irradiation. Apoptosis is induced by interluekin 24 in melanoma cells.
Documents
Related products
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.