HLA class I histocompatibility antigen, alpha chain E Antibody
Catalog no. HLAE-101AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
HLAE-101AP — affinity purified Rabbit antibody against HLA E. Validated for ELISA, WB. Reacts with Human.
Specifications
| Catalog number | HLAE-101AP |
|---|---|
| Target | HLA E |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human |
| Applications | ELISA, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 71-120 on HLA class I histocompatibility antigen, alpha chain E protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P13747 |
About this target
HLA class I histocompatibility antigen, alpha chain E Antibody (HLAE-101AP) is an affinity-purified rabbit polyclonal antibody against HLA E. It is listed for ELISA, WB and reacts with Human. For research use only. Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglobulin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molecules (VL9 peptides - VMAPRT[V/L][L/V/I/F]L). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1, enabling NK cells to monitor the expression of other MHC class I molecules in healthy cells and to tolerate self. Subcellular location: Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane.; SUBCELLULAR LOCATION: [Soluble HLA class I histocompatibility antigen, alpha chain E]: Secreted.
Documents
Related products
- HLA class I histocompatibility antigen, alpha chain E Antibody BIOTIN (HLAE-BIOTIN)
- HLA class I histocompatibility antigen, alpha chain E Antibody FITC (HLAE-FITC)
- HLA class I histocompatibility antigen, alpha chain E Blocking Peptide (P-HLAE)
- HLA class I histocompatibility antigen, alpha chain E Antibody Positve Control (PC-HLAE)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.