HLA class I histocompatibility antigen, alpha chain E Blocking Peptide
Catalog no. P-HLAE · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-HLAE — affinity-purified Rabbit antibody against HLA E. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-HLAE |
|---|---|
| Target | HLA E |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 71-120 on HLA class I histocompatibility antigen, alpha chain E protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | P13747 |
About this target
HLA class I histocompatibility antigen, alpha chain E Blocking Peptide is the antigenic blocking peptide for the HLA E antibody HLAE-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglobulin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molecules (VL9 peptides - VMAPRT[V/L][L/V/I/F]L). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1, enabling NK cells to monitor the expression of other MHC class I molecules in healthy cells and to tolerate self. Subcellular location: Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane.; SUBCELLULAR LOCATION: [Soluble HLA class I histocompatibility antigen, alpha chain E]: Secreted.
Documents
Related products
- HLA class I histocompatibility antigen, alpha chain E Antibody (HLAE-101AP)
- HLA class I histocompatibility antigen, alpha chain E Antibody BIOTIN (HLAE-BIOTIN)
- HLA class I histocompatibility antigen, alpha chain E Antibody FITC (HLAE-FITC)
- HLA class I histocompatibility antigen, alpha chain E Antibody Positve Control (PC-HLAE)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.