HLA class I histocompatibility antigen, alpha chain E Antibody Positve Control
Catalog no. PC-HLAE · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-HLAE — affinity-purified Rabbit antibody against HLA E. Validated for WB.
Specifications
| Catalog number | PC-HLAE |
|---|---|
| Target | HLA E |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | P13747 |
About this target
HLA class I histocompatibility antigen, alpha chain E Antibody Positve Control is a Western blot positive control for HLA E antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Non-classical major histocompatibility class Ib molecule involved in immune self-nonself discrimination. In complex with B2M/beta-2-microglobulin binds nonamer self-peptides derived from the signal sequence of classical MHC class Ia molecules (VL9 peptides - VMAPRT[V/L][L/V/I/F]L). Peptide-bound HLA-E-B2M heterotrimeric complex primarily functions as a ligand for natural killer (NK) cell inhibitory receptor KLRD1-KLRC1, enabling NK cells to monitor the expression of other MHC class I molecules in healthy cells and to tolerate self. Subcellular location: Cell membrane; Single-pass type I membrane protein. Golgi apparatus membrane.; SUBCELLULAR LOCATION: [Soluble HLA class I histocompatibility antigen, alpha chain E]: Secreted.
Documents
Related products
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- HLA class I histocompatibility antigen, alpha chain E Blocking Peptide (P-HLAE)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.