Phospho-MLKL Antibody
Catalog no. PMLKL-140AP · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
PMLKL-140AP — affinity purified Rabbit antibody against Phospho-MLKL. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | PMLKL-140AP |
|---|---|
| Target | Phospho-MLKL |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 350-400 on human Mixed lineage kinase domain-like protein MLKL |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q8NB16 |
About this target
Phospho-MLKL Antibody (PMLKL-140AP) is an affinity-purified rabbit polyclonal antibody against Phospho-MLKL. It is listed for ELISA, IP, WB and reacts with Human, Mouse, Rat. For research use only. Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Subcellular location: Cytoplasm. Cell membrane. Nucleus. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction. Localizes to the nucleus in response to orthomyxoviruses infection.
Documents
Related products
- Phospho-MLKL Blocking Peptide (P-PMLKL)
- Phospho-MLKL Positive Control (PC-PMLKL)
- Phospho-MLKL Antibody BIOTIN (PMLKL-BIOTIN)
- Phospho-MLKL Antibody FITC (PMLKL-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.