Phospho-MLKL Blocking Peptide
Catalog no. P-PMLKL · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-PMLKL — affinity-purified Rabbit antibody against Phospho-MLKL. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-PMLKL |
|---|---|
| Target | Phospho-MLKL |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 350-400 on human Mixed lineage kinase domain-like protein MLKL |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q8NB16 |
About this target
Phospho-MLKL Blocking Peptide is the antigenic blocking peptide for the Phospho-MLKL antibody PMLKL-140AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Subcellular location: Cytoplasm. Cell membrane. Nucleus. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction. Localizes to the nucleus in response to orthomyxoviruses infection.
Documents
Related products
- Phospho-MLKL Positive Control (PC-PMLKL)
- Phospho-MLKL Antibody (PMLKL-140AP)
- Phospho-MLKL Antibody BIOTIN (PMLKL-BIOTIN)
- Phospho-MLKL Antibody FITC (PMLKL-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.