Phospho-MLKL Positive Control
Catalog no. PC-PMLKL · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-PMLKL — affinity-purified Rabbit antibody against Phospho-MLKL. Validated for WB.
Specifications
| Catalog number | PC-PMLKL |
|---|---|
| Target | Phospho-MLKL |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q8NB16 |
About this target
Phospho-MLKL Positive Control is a Western blot positive control for Phospho-MLKL antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Pseudokinase that plays a key role in TNF-induced necroptosis, a programmed cell death process. Does not have protein kinase activity. Activated following phosphorylation by RIPK3, leading to homotrimerization, localization to the plasma membrane and execution of programmed necrosis characterized by calcium influx and plasma membrane damage. Subcellular location: Cytoplasm. Cell membrane. Nucleus. Note=Localizes to the cytoplasm and translocates to the plasma membrane on necroptosis induction. Localizes to the nucleus in response to orthomyxoviruses infection.
Documents
Related products
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- Phospho-MLKL Antibody FITC (PMLKL-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.