SPOP Antibody BIOTIN
Catalog no. SPOP-BIOTIN · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
SPOP-BIOTIN — affinity purified Rabbit antibody against SPOP. Validated for ELISA, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | SPOP-BIOTIN |
|---|---|
| Target | SPOP |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 325-374 on human SPOP protein. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | O43791 |
About this target
SPOP Antibody BIOTIN is the biotin-conjugated version of the SPOP antibody SPOP-101AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. Subcellular location: Nucleus. Nucleus speckle. Cytoplasm.
Documents
Related products
- SPOP Blocking Peptide (P-SPOP)
- SPOP Positive Control (PC-SPOP)
- SPOP Antibody (SPOP-101AP)
- SPOP Antibody FITC (SPOP-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.