SPOP Blocking Peptide
Catalog no. P-SPOP · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-SPOP — affinity-purified Rabbit antibody against SPOP. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-SPOP |
|---|---|
| Target | SPOP |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide corresponding to amino acids within region 325-374 on human SPOP protein. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | O43791 |
About this target
SPOP Blocking Peptide is the antigenic blocking peptide for the SPOP antibody SPOP-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. Subcellular location: Nucleus. Nucleus speckle. Cytoplasm.
Documents
Related products
- SPOP Positive Control (PC-SPOP)
- SPOP Antibody (SPOP-101AP)
- SPOP Antibody BIOTIN (SPOP-BIOTIN)
- SPOP Antibody FITC (SPOP-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.