SPOP Positive Control
Catalog no. PC-SPOP · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-SPOP — affinity-purified Rabbit antibody against SPOP. Validated for WB.
Specifications
| Catalog number | PC-SPOP |
|---|---|
| Target | SPOP |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | O43791 |
About this target
SPOP Positive Control is a Western blot positive control for SPOP antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Component of a cullin-RING-based BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex that mediates the ubiquitination of target proteins, leading most often to their proteasomal degradation. In complex with CUL3, involved in ubiquitination and proteasomal degradation of BRMS1, DAXX, PDX1/IPF1, GLI2 and GLI3. In complex with CUL3, involved in ubiquitination of MACROH2A1 and BMI1; this does not lead to their proteasomal degradation. Inhibits transcriptional activation of PDX1/IPF1 targets, such as insulin, by promoting PDX1/IPF1 degradation. Subcellular location: Nucleus. Nucleus speckle. Cytoplasm.
Documents
Related products
- SPOP Blocking Peptide (P-SPOP)
- SPOP Antibody (SPOP-101AP)
- SPOP Antibody BIOTIN (SPOP-BIOTIN)
- SPOP Antibody FITC (SPOP-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.