CXCR2 Antibody
Catalog no. CXCR2-221AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
CXCR2-221AP — affinity purified Rabbit antibody against CXCR2. Validated for ELISA, IP, WB. Reacts with Mouse, Rat.
Specifications
| Catalog number | CXCR2-221AP |
|---|---|
| Target | CXCR2 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Mouse, Rat |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide corresponding to amino acids within region 300-352 on mouse C-X-C Chemokine Receptot type 2. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | P35343 |
About this target
CXCR2 Antibody (CXCR2-221AP) is an affinity-purified rabbit polyclonal antibody against CXCR2. It is listed for ELISA, IP, WB and reacts with Mouse, Rat. For research use only. Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Involved in the homeostatic wound healing response to tissue injury, a multistep cascade that guides neutrophil migration to necrotic sites while avoiding collateral damage of healthy tissues. Signals intravascular neutrophil chemotaxis to the injury site. Subcellular location: Cell membrane; Multi-pass membrane protein.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.