CXCR2 Positive Control
Catalog no. PC-CXCR2-221 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-CXCR2-221 — affinity-purified Rabbit antibody against CXCR2. Validated for WB.
Specifications
| Catalog number | PC-CXCR2-221 |
|---|---|
| Target | CXCR2 |
| Applications | WB |
| Conjugate | Unconjugated |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | P35343 |
About this target
CXCR2 Positive Control is a Western blot positive control for CXCR2 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Receptor for interleukin-8 which is a powerful neutrophil chemotactic factor. Binding of IL-8 to the receptor causes activation of neutrophils. This response is mediated via a G protein that activates a phosphatidylinositol-calcium second messenger system. Binds to IL-8 with high affinity. Also binds with high affinity to CXCL3, GRO/MGSA and NAP-2. Involved in the homeostatic wound healing response to tissue injury, a multistep cascade that guides neutrophil migration to necrotic sites while avoiding collateral damage of healthy tissues. Signals intravascular neutrophil chemotaxis to the injury site. Subcellular location: Cell membrane; Multi-pass membrane protein.
Documents
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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.