MOTS-c Antibody
Catalog no. MOTSC-101AP · Research Use Only
$320 per 100 µg. Ships within 2–3 business days from the U.S.
MOTSC-101AP — affinity purified Rabbit antibody against MOTS-c. Validated for ELISA, IHC, IP, WB. Reacts with Human, Mouse, Rat.
Specifications
| Catalog number | MOTSC-101AP |
|---|---|
| Target | MOTS-c |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse, Rat |
| Applications | ELISA, IHC, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Full-length peptide corresponding to amino acids 1-16 on MOTS-c. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | A0A0C5B5G6 |
About this target
MOTS-c Antibody (MOTSC-101AP) is an affinity-purified rabbit polyclonal antibody against MOTS-c. It is listed for ELISA, IHC, IP, WB and reacts with Human, Mouse, Rat. For research use only. Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity. Subcellular location: Secreted. Mitochondrion. Nucleus. Note=Translocates to the nucleus in response to metabolic stress in an AMPK-dependent manner.
Documents
Related products
- MOTS-c Antibody BIOTIN (MOTSC-BIOTIN)
- MOTS-c Antibody FITC (MOTSC-FITC)
- MOTS-c Blocking Peptide (P-MOTSC)
- MOTS-c Positive Control (PC-MOTSC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.