MOTS-c Antibody BIOTIN
Catalog no. MOTSC-BIOTIN · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
MOTSC-BIOTIN — affinity purified Rabbit antibody against MOTS-c. Validated for ELISA, IHC, IP, WB. Reacts with Human, Rat.
Specifications
| Catalog number | MOTSC-BIOTIN |
|---|---|
| Target | MOTS-c |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Rat |
| Applications | ELISA, IHC, IP, WB |
| Conjugate | BIOTIN |
| Purity | Affinity Purified |
| Immunogen | Full-length peptide corresponding to amino acids 1-16 on MOTS-c. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | A0A0C5B5G6 |
About this target
MOTS-c Antibody BIOTIN is the biotin-conjugated version of the MOTS-c antibody MOTSC-101AP, an affinity-purified rabbit polyclonal used in ELISA, IHC, IP, WB and reactive with Human, Rat. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity. Subcellular location: Secreted. Mitochondrion. Nucleus. Note=Translocates to the nucleus in response to metabolic stress in an AMPK-dependent manner.
Documents
Related products
- MOTS-c Antibody (MOTSC-101AP)
- MOTS-c Antibody FITC (MOTSC-FITC)
- MOTS-c Blocking Peptide (P-MOTSC)
- MOTS-c Positive Control (PC-MOTSC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.