MOTS-c Positive Control

Catalog no. PC-MOTSC · Research Use Only

$220 per 5 applications. Ships within 2–3 business days from the U.S.

PC-MOTSC — affinity-purified Rabbit antibody against MOTS-c. Validated for WB.

Specifications

Catalog numberPC-MOTSC
TargetMOTS-c
ApplicationsWB
ConjugateUnconjugated
Size5 applications
Storage-20°C
UniProtA0A0C5B5G6

About this target

MOTS-c Positive Control is a Western blot positive control for MOTS-c antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity. Subcellular location: Secreted. Mitochondrion. Nucleus. Note=Translocates to the nucleus in response to metabolic stress in an AMPK-dependent manner.

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FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.