MOTS-c Blocking Peptide
Catalog no. P-MOTSC · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-MOTSC — affinity-purified Rabbit antibody against MOTS-c. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-MOTSC |
|---|---|
| Target | MOTS-c |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Full-length peptide corresponding to amino acids 1-16 on MOTS-c. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | A0A0C5B5G6 |
About this target
MOTS-c Blocking Peptide is the antigenic blocking peptide for the MOTS-c antibody MOTSC-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Regulates insulin sensitivity and metabolic homeostasis. Inhibits the folate cycle, thereby reducing de novo purine biosynthesis which leads to the accumulation of the de novo purine synthesis intermediate 5-aminoimidazole-4-carboxamide (AICAR) and the activation of the metabolic regulator 5'-AMP-activated protein kinase (AMPK). Protects against age-dependent and diet-induced insulin resistance as well as diet-induced obesity. Subcellular location: Secreted. Mitochondrion. Nucleus. Note=Translocates to the nucleus in response to metabolic stress in an AMPK-dependent manner.
Documents
Related products
- MOTS-c Antibody (MOTSC-101AP)
- MOTS-c Antibody BIOTIN (MOTSC-BIOTIN)
- MOTS-c Antibody FITC (MOTSC-FITC)
- MOTS-c Positive Control (PC-MOTSC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.