PI3R6 Antibody
Catalog no. PIK3R6-101AP · Research Use Only
$285 per 100 µg. Ships within 2–3 business days from the U.S.
PIK3R6-101AP — affinity purified Rabbit antibody against PI3R6. Validated for ELISA, IP, WB. Reacts with Human, Mouse.
Specifications
| Catalog number | PIK3R6-101AP |
|---|---|
| Target | PI3R6 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, IP, WB |
| Conjugate | Unconjugated |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 590-640 on human PhosphoInositide 3-kinase regulatory subunit 6. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q5UE93 |
About this target
PI3R6 Antibody (PIK3R6-101AP) is an affinity-purified rabbit polyclonal antibody against PI3R6. It is listed for ELISA, IP, WB and reacts with Human, Mouse. For research use only. Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Translocated to the plasma membrane in a Ras-dependent manner.
Documents
Related products
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- PI3R6 Antibody BIOTIN (PIK3R6-BIOTIN)
- PI3R6 Antibody FITC (PIK3R6-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.