PI3R6 Blocking Peptide
Catalog no. P-PIK3R6 · Research Use Only
$155 per 250 µg. Ships within 2–3 business days from the U.S.
P-PIK3R6 — affinity-purified Rabbit antibody against PI3R6. Validated for Immunodepletion, Immunocompetition.
Specifications
| Catalog number | P-PIK3R6 |
|---|---|
| Target | PI3R6 |
| Applications | Immunodepletion, Immunocompetition |
| Conjugate | Unconjugated |
| Immunogen | Synthetic peptide taken within amino acid region 590-640 on human PhosphoInositide 3-kinase regulatory subunit 6. |
| Size | 250 µg |
| Storage | -20°C |
| UniProt | Q5UE93 |
About this target
PI3R6 Blocking Peptide is the antigenic blocking peptide for the PI3R6 antibody PIK3R6-101AP. Pre-incubating the antibody with the peptide competes away specific binding, which helps confirm that a signal comes from the intended target. Supplied at 250 µg, for research use only. Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Translocated to the plasma membrane in a Ras-dependent manner.
Documents
Related products
- PI3R6 Positive Control (PC-PIK3R6)
- PI3R6 Antibody (PIK3R6-101AP)
- PI3R6 Antibody BIOTIN (PIK3R6-BIOTIN)
- PI3R6 Antibody FITC (PIK3R6-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.