PI3R6 Positive Control
Catalog no. PC-PIK3R6 · Research Use Only
$200 per 5 applications. Ships within 2–3 business days from the U.S.
PC-PIK3R6 — affinity-purified Rabbit antibody against PI3R6. Validated for WB.
Specifications
| Catalog number | PC-PIK3R6 |
|---|---|
| Target | PI3R6 |
| Applications | WB |
| Conjugate | Unconjugated |
| Immunogen | Purified protein. |
| Size | 5 applications |
| Storage | -20°C |
| UniProt | Q5UE93 |
About this target
PI3R6 Positive Control is a Western blot positive control for PI3R6 antibodies. It gives a reference band to confirm the antibody and the blotting procedure are working. Supplied for 5 applications, for research use only. Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Translocated to the plasma membrane in a Ras-dependent manner.
Documents
Related products
- PI3R6 Blocking Peptide (P-PIK3R6)
- PI3R6 Antibody (PIK3R6-101AP)
- PI3R6 Antibody BIOTIN (PIK3R6-BIOTIN)
- PI3R6 Antibody FITC (PIK3R6-FITC)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.