PI3R6 Antibody FITC
Catalog no. PIK3R6-FITC · Research Use Only
$375 per 100 µg. Ships within 2–3 business days from the U.S.
PIK3R6-FITC — affinity purified Rabbit antibody against PI3R6. Validated for ELISA, IP, WB. Reacts with Human, Mouse.
Specifications
| Catalog number | PIK3R6-FITC |
|---|---|
| Target | PI3R6 |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | IgG |
| Reactivity | Human, Mouse |
| Applications | ELISA, IP, WB |
| Conjugate | FITC |
| Purity | Affinity Purified |
| Immunogen | Synthetic peptide taken within amino acid region 590-640 on human PhosphoInositide 3-kinase regulatory subunit 6. |
| Size | 100 µg |
| Storage | -20°C |
| UniProt | Q5UE93 |
About this target
PI3R6 Antibody FITC is the FITC-conjugated version of the PI3R6 antibody PIK3R6-101AP, an affinity-purified rabbit polyclonal used in ELISA, IP, WB and reactive with Human, Mouse. The conjugate removes the need for a labeled secondary antibody in direct detection. For research use only. Regulatory subunit of the PI3K gamma complex. Acts as an adapter to drive activation of PIK3CG by beta-gamma G protein dimers. The PIK3CG:PIK3R6 heterodimer is much less sensitive to beta-gamma G protein dimers than PIK3CG:PIK3R5 and its membrane recruitment and beta-gamma G protein dimer-dependent activation requires HRAS bound to PIK3CG. Recruits of the PI3K gamma complex to a PDE3B:RAPGEF3 signaling complex involved in angiogenesis; signaling seems to involve RRAS. Subcellular location: Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Translocated to the plasma membrane in a Ras-dependent manner.
Documents
Related products
- PI3R6 Blocking Peptide (P-PIK3R6)
- PI3R6 Positive Control (PC-PIK3R6)
- PI3R6 Antibody (PIK3R6-101AP)
- PI3R6 Antibody BIOTIN (PIK3R6-BIOTIN)
FabGennix International, Inc., 9191 Kyser Way, Frisco, TX 75033. For research use only. Not for diagnostic or therapeutic use.