General Information |
|
Product |
SIGLEC10 Antibody FITC-Conjugated |
Description |
FITC-Conjugated Sialic acid-binding Ig-like lectin 10 Antibody |
Verified Applications |
ELISA, IP, WB |
Host |
Rabbit |
Species Cross Reactivity |
Human, Rat |
Immunogen |
Synthetic peptide taken within amino acid region 650-697 on human SIGLEC10 protein. |
Accession # |
NCBI: NP_149121.2 |
|
|
Quantity |
100 µg |
Volume |
200 µl |
Concentration |
0.56-0.60 µg/µl in antibody stabilization buffer |
Form |
FITC-Conjugated |
Clonality |
Polyclonal |
Storage |
-20⁰C for long term storage |
|
|
ELISA |
1:10,000 |
Immunoprecipitation | 1:200 |
Western Blot |
1:500 |
|
|
Uniprot # |
|
Overview |
Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- or alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. |
Molecular Function |
carbohydrate binding |
Subcellular Location |
Isoform 1,2,3,4: cell membrane, single-pass type I membrane protein; isoform 5: secreted |
Expression |
Expressed by peripheral blood leukocytes (eosinophils, monocytes and a natural killer cell subpopulation). Isoform5 is found to be the most abundant isoform. Found in lymph node, lung, ovary and appendix. Isoform 1 is found at high levels and isoform 2 at lower levels in bone marrow, spleen and spinal chord. Isoform 2 is also found in brain. Isoform 4 is specifically found in natural killer cells. |
Alternative Nomenclature |
PRO940 antibody sialic acid binding Ig like lectin 10 Ig like lectin 7 antibody Sialic acid binding Immunoglobulin like lectin 10 antibody Sialic acid-binding Ig-like lectin 10 antibody SIGLEC 10 antibody Siglec G antibody Siglec-like protein 2 antibody SIGLEC10 antibody Siglecg antibody SLG2 antibody |
Protein information supplied by UniProt
Product | Note | Status | Price | |
---|---|---|---|---|
|
SIGLEC10-101AP | |||
|
P-SIGLEC10 | |||
|
SIGLEC10-BIOTIN | |||
|
PC-SIGLEC10 | |||
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